Apoptosis ELISA kits are ready-to-use, antibody-based assays designed to measure specific proteins involved in programmed cell death. As apoptosis is a carefully regulated process, a large number of different proteins and enzymes may be of particular interest.

In the extrinsic pathway, cytokines such as TNF alpha and Fas ligand interact with receptors of the TNF family and proteins in the death domain to trigger the caspase cascade, beginning with caspase 8. In the intrinsic pathway, Members of the Bcl-2 family and IAP can drive or inhibit mitochondrial permeability and cytochrome c release into the cytoplasm. This leads to apoptosome formation and activation of caspase 9.

Alternative proteins can also be found; just visit any page of the APOPTOSIS ELISA kit and enter a name in the text box. Then use the filters provided to help narrow your search.

ELISA (Enzyme-Linked Immunosorbent Assay) is a widely used application for detecting and quantifying proteins and antigens from various samples. Target-specific ELISA kits are available from a variety of manufacturers and can help optimize your immunodetection experiments.